Intraepithelial carcinoma (Bowen disease)
☆ 2022 ۾ جرمني مان Stiftung Warentest نتيجن، ModelDerm سان صارفين جي اطمينان صرف ادا ڪيل ٽيلي ميڊيسن مشوري جي ڀيٽ ۾ ٿورو گهٽ هئي.
عام صورت ― Intraepithelial carcinoma (Bowen disease) غلط تشخيص ٿي سگھي ٿي ھڪڙي ڊگھي، غير خارش واري ايجما جي طور تي.
References
Bowen's disease (BD) چمڙي جي ڪينسر جو هڪ قسم آهي جيڪو چمڙي جي ٻاهرئين پرت (ايپيڊرميس) ۾ شروع ٿئي ٿو. اهو Caucasians ۾ وڌيڪ عام آهي ۽ اڪثر ڪري انهن علائقن ۾ ٿئي ٿو جيڪي سج جي روشنيءَ جي سامهون آهن، پر اهو ٻئي هنڌ به ظاهر ٿي سگهي ٿو. BD عام طور تي هڪ واحد زخم جي طور تي ظاهر ٿئي ٿو. BD اڪثر ڪري هڪ ڊيڄاريندڙ نشاني جي طور تي ڏٺو ويندو آهي ان کان اڳ جو هڪ وڌيڪ سنگين قسم جي چمڙي جي ڪينسر جي ترقي. BD جي تشخيص ڪرڻ لاءِ، ڊاڪٽر عام طور تي خوردبيني (بايوپسي) هيٺ ٽشو جي نمونن جي جانچ ڪرڻ تي ڀاڙين ٿا.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease گهڻو ڪري 60 سالن کان مٿي عمر جي اڇي ماڻهن کي متاثر ڪري ٿو. اهم خطرن جا عنصر شامل آهن ڊگهي عرصي تائين سج جي نمائش، ڪمزور مدافعتي نظام، ارسنڪ جي نمائش، ۽ چمڙي جي ايڇ وي وي انفيڪشن. HPV strains 16، 18، 34، ۽ 48 جينياتي علائقن ۾ Bowen جي بيماري سان ڳنڍيل آهن. غير جينياتي ڪيسن ۾ HPV جي شموليت گهٽ واضح آهي.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
اهو عام طور تي جسم تي ڪٿي به هڪ erythematous، scally يا crusty علائقي جي طور تي ظاهر ٿئي ٿو. سڀ کان وڌيڪ عام جڳهه هيٺيون ٽنگون آهن.
اهو علاج جي مختلف طريقن سان قابل علاج آهي جهڙوڪ ڪريوٿراپي، ڪيوريٽج، ڪيٽري، فوٽوڊينامڪ تھراپي، يا زخم کي ختم ڪرڻ.
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